牛血清白蛋白 來源于牛血清

牛血清白蛋白 來源于牛血清

性質

Related Categories Albumin, Bovine Serum Albumins,Chromatographically Purified, New Zealand Origin Bovine Serum Albumins, 生化試劑,
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biological source   bovine
assay   ≥98% (agarose gel electrophoresis)
form   lyophilized powder
mol wt   ~66 kDa
packaging   poly bottle of
impurities   ≤0.01% free fatty acid (GC)
pH   4.8-7.5
solubility   H2O: soluble 40 mg/mL
storage temp.   2-8°C

折疊

產品描述

包裝

1 kg in poly bottle

1, 25, 100 g in poly bottle

Preparation Note

Sourced and manufactured in New Zealand

prepared by chromatography

血清白蛋白可能也會被稱為Fraction V。該命名慣例取自使用冷乙醇沉淀對血清蛋白進行分級的原始Cohn法。 血清白蛋白可在采用Cohn′s法的第五乙醇分級中發(fā)現。 從此，有些人便開始使用“Fraction V”這一術語來描述血清白蛋白，無論使用的是什么制備方法。 也有人在使用該術語來描述通過乙醇分級方法而純化得到血清白蛋白，而這種方法是相對于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生產和分銷從各種主要方法純化得到的血清白蛋白，包括真正的Cohn分級法、改良的乙醇分級方法、熱休克和色譜法。 更多的純化步驟包括結晶或木炭過濾。

Application

Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry. [2]

Biochem/physiol Actions

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals. [1]

BSA的某些構象和初級序列表位是人類對牛肉和牛奶過敏中的可疑過敏原。

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein has an amazing ability to bind to ligands. [1]